This volume emerges from the "Design Research Streams" lecture series at Sapienza University of Rome, showcasing innovative research directions in contemporary design through the voices of ten emerging Italian scholars. From posthuman design education integrating artificial intelligence to immersive technologies transforming communication, from generative manufacturing processes to biodesign practices collaborating with living organisms, these contributions reveal how design is redefining its boundaries and methodologies. Organized in three sections - Perspectives, Visions, and Streams - the book presents both theoretical frameworks and applied experimentations that address the challenges of our time: sustainability, transdisciplinarity, and emerging technologies. A compelling snapshot of where Italian design research is heading, offering essential insights for designers, researchers, and anyone seeking to understand how the discipline is evolving in response to contemporary complexities.