This volume presents the proceedings of the Conference The Future of Hope: an Interdisciplinary Dialogue, promoted by the European University of Rome in Brussels in 2024 as part of the journey toward the Jubilee 2025. Hope is explored as a dynamic concept: rooted in biblical and philosophical traditions yet crucial for today's challenges-artificial intelligence, migration, peace, education, sustainability, and innovation. The collected essays combine scientific rigor with dialogue between academia and politics, showing how hope can inspire critical reflection and concrete action, revealing possibilities of truth and goodness even in complex times.