Strategic innovation enables firms to redefine how they do business, deliver greater value, and remain cost-effective. It allows companies to stay competitive and achieve profitable growth, even in unstable and uncertain environments. This book introduces an original model of the strategic innovation process, developed through a multiple case study analysis of four global firms. Top management plays a key role in shaping innovative strategies and reinforcing them with targeted organizational actions that foster entrepreneurial behavior. Proactively cultivating a distinctive resource portfolio is essential for se-curing competitive advantage in the design and implementation of strategic innovation.